We've done insane can't-play-your-normals before.
A long time from now, in a Universe very, very close:
All of our characters were born the opposite gender.
You get the idea.
Out ladies are transporting a delegation of some people to some kind of event. These passengers come from a deeply misogynistic world - they barely acknowledge women, forget respect. There have been a number of pinched asses, suggestive hand motions and even some aspersions cast on the manliness of the men. (Jon Rand would like you to know that his hair is a mirror of his genitals - large and basket-shaped. IDK.)
And just to make your lives
The idea is not to play BRAND NEW characters, but to step away from the ones you love - try some others on, see how they fit. Lurkerrrrs, this is a great game for you, you can be ANYONE.
WHAT A TWIST!!